ALOX5 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: arachidonate 5-lipoxygenase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68-78 kDa
Uniprot: P09917
Gene id:
Background: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, WB
Dilution: WB: 1:200-1:2000; IF: 1:20-1:100
Target: ALOX5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: arachidonate 5-lipoxygenase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68-78 kDa
Uniprot: P09917
Gene id:
Background: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, WB
Dilution: WB: 1:200-1:2000; IF: 1:20-1:100
Target: ALOX5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat