EIF4EBP1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 6C4
Isotype: IgG2b
Immunogen: eukaryotic translation initiation factor 4E binding protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 12 kDa
Uniprot: Q13541
Gene id: 1978
Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: EIF4EBP1
Purification: Protein A+G purification
Reactivity: Human
Clonality: Monoclonal
Clone: 6C4
Isotype: IgG2b
Immunogen: eukaryotic translation initiation factor 4E binding protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 12 kDa
Uniprot: Q13541
Gene id: 1978
Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: EIF4EBP1
Purification: Protein A+G purification
Reactivity: Human