GNA13 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: guanine nucleotide binding protein (G protein), alpha 13
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: Guanine nucleotide-binding proteins (G proteins are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1
p115RhoGEF, ARHGEF11
PDZ-RhoGEF and ARHGEF12
LARG. GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1 (By similarity. Promotes tumor cell invasion and metastasis by activating RhoA
ROCK signaling pathway. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation.
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Target: GNA13
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: guanine nucleotide binding protein (G protein), alpha 13
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: Guanine nucleotide-binding proteins (G proteins are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1
p115RhoGEF, ARHGEF11
PDZ-RhoGEF and ARHGEF12
LARG. GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1 (By similarity. Promotes tumor cell invasion and metastasis by activating RhoA
ROCK signaling pathway. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation.
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Target: GNA13
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat