GSDMD antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone:
Isotype: IgG2a
Immunogen: gasdermin D
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:1000-1:5000; IF: 1:20-1:200
Target: GSDMD
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone:
Isotype: IgG2a
Immunogen: gasdermin D
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:1000-1:5000; IF: 1:20-1:200
Target: GSDMD
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat