CD3E antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CD3e molecule, epsilon (CD3-TCR complex)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 23-25 kDa
Uniprot: P07766
Gene id: 916
Background: CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR
CD3 complex of T-lymphocytes consists of either a TCR alpha
beta or TCR gamma
delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.
Field of research: Cancer, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500 - 1:2000
Target: CD3E
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CD3e molecule, epsilon (CD3-TCR complex)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 23-25 kDa
Uniprot: P07766
Gene id: 916
Background: CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR
CD3 complex of T-lymphocytes consists of either a TCR alpha
beta or TCR gamma
delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.
Field of research: Cancer, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500 - 1:2000
Target: CD3E
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat