HLA-G antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 3C12
Isotype: IgG1
Immunogen: MHC class I antigen G
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: P17693
Gene id: 3135
Background: Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Field of research: Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:2000-1:10000; IHC: 1:50-1:200
Target: HLA-G
Purification: protein A+G purified
Reactivity: Human
![]()
Clonality: Monoclonal
Clone: 3C12
Isotype: IgG1
Immunogen: MHC class I antigen G
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: P17693
Gene id: 3135
Background: Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Field of research: Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:2000-1:10000; IHC: 1:50-1:200
Target: HLA-G
Purification: protein A+G purified
Reactivity: Human