SNCA antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 5C6
Isotype: IgG1
Immunogen: synuclein, alpha (non A4 component of amyloid precursor)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: P37840
Gene id: 6622
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Target: SNCA
Purification: protein A+G purified
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 5C6
Isotype: IgG1
Immunogen: synuclein, alpha (non A4 component of amyloid precursor)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: P37840
Gene id: 6622
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Target: SNCA
Purification: protein A+G purified
Reactivity: Human, Mouse, Rat