SQSTM1 antibody - 100 µg
Host : mouse
Clonality: Monoclonal
Clone: 5H3
Isotype: IgG2a
Immunogen: sequestosome 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 62 kDa
Uniprot: Q13501
Gene id: 8878
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding
adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Field of research: Neuroscience, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200
Target: SQSTM1
Purification: protein A+G purified
Reactivity: Human
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Clonality: Monoclonal
Clone: 5H3
Isotype: IgG2a
Immunogen: sequestosome 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 62 kDa
Uniprot: Q13501
Gene id: 8878
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding
adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Field of research: Neuroscience, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200
Target: SQSTM1
Purification: protein A+G purified
Reactivity: Human