TLR4 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 3E7
Isotype: IgG2b
Immunogen: toll-like receptor 4
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 100 kDa
Uniprot: O00206
Gene id: 7099
Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Field of research: Neuroscience, Immunology, Signal Transduction, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:8000; IHC: 1:50-1:500
Target: TLR4
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 3E7
Isotype: IgG2b
Immunogen: toll-like receptor 4
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 100 kDa
Uniprot: O00206
Gene id: 7099
Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Field of research: Neuroscience, Immunology, Signal Transduction, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:8000; IHC: 1:50-1:500
Target: TLR4
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat