CYCS antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 3G4
Isotype: IgG2a
Immunogen: Cytochrome c
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 12 kDa
Uniprot: P99999
Gene id: 54205
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:5000-1:30000; IHC: 1:100-1:1000
Target: CYCS
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 3G4
Isotype: IgG2a
Immunogen: Cytochrome c
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 12 kDa
Uniprot: P99999
Gene id: 54205
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:5000-1:30000; IHC: 1:100-1:1000
Target: CYCS
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat