CCL20 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: chemokine(C-C motif) ligand 20
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: P78556
Gene id:
Background: CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17(Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells(DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease(COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:50-1:500
Target: CCL20
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: chemokine(C-C motif) ligand 20
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: P78556
Gene id:
Background: CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17(Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells(DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease(COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:50-1:500
Target: CCL20
Purification: Immunogen affinity purified
Reactivity: Human