ZNF658 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: zinc finger protein 658
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 71 kDa
Uniprot: Q5TYW1
Gene id: 26149
Background: Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element(ZTRE)(5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: ZNF658
Purification: Immunogen affinity purified
Reactivity: Human, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: zinc finger protein 658
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 71 kDa
Uniprot: Q5TYW1
Gene id: 26149
Background: Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element(ZTRE)(5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: ZNF658
Purification: Immunogen affinity purified
Reactivity: Human, Rat