ZBTB38 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: zinc finger and BTB domain containing 38
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 134 kDa
Uniprot: Q8NAP3
Gene id: 253461
Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and
or survival of late postmitotic neurons(By similarity).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: ZBTB38
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: zinc finger and BTB domain containing 38
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 134 kDa
Uniprot: Q8NAP3
Gene id: 253461
Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and
or survival of late postmitotic neurons(By similarity).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: ZBTB38
Purification: Immunogen affinity purified
Reactivity: Human