YWHAB antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: tyrosine 3-monooxygenase
tryptophan 5-monooxygenase activation protein, beta polypeptide
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 28 kDa
Uniprot: P31946
Gene id: 7529
Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
Field of research: Neuroscience, Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20-1:200
Target: YWHAB
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

235.85 € 235.85 EUR 235.85 € VAT Excluded

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