VPS8 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: vacuolar protein sorting 8 homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 151 kDa
Uniprot: Q8N3P4
Gene id: 23355
Background: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A
B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF,IP
Dilution: WB: 1:500-1:5000;IP: 1:200-1:2000; IF: 1:10-1:100
Target: VPS8
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: vacuolar protein sorting 8 homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 151 kDa
Uniprot: Q8N3P4
Gene id: 23355
Background: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A
B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF,IP
Dilution: WB: 1:500-1:5000;IP: 1:200-1:2000; IF: 1:10-1:100
Target: VPS8
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat