VPS33B antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: vacuolar protein sorting 33 homolog B(yeast)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 71 kDa
Uniprot: Q9H267
Gene id: 26276
Background: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking
fusion reactions of late endosomes
lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Target: VPS33B
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat, Zebrafish
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: vacuolar protein sorting 33 homolog B(yeast)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 71 kDa
Uniprot: Q9H267
Gene id: 26276
Background: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking
fusion reactions of late endosomes
lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Target: VPS33B
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat, Zebrafish