UVRAG antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: UV radiation resistance associated gene
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 100 kDa
Uniprot: Q9P2Y5
Gene id: 7405
Background: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Target: UVRAG
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: UV radiation resistance associated gene
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 100 kDa
Uniprot: Q9P2Y5
Gene id: 7405
Background: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Target: UVRAG
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat