USP37 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ubiquitin specific peptidase 37
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 110 kDa, 70 kDa
Uniprot: Q86T82
Gene id: 57695
Background: Deubiquitinase that antagonizes the anaphase-promoting complex(APC
C) during G1
S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC
C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1
S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
Field of research: Epigenetics, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000
Target: USP37
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ubiquitin specific peptidase 37
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 110 kDa, 70 kDa
Uniprot: Q86T82
Gene id: 57695
Background: Deubiquitinase that antagonizes the anaphase-promoting complex(APC
C) during G1
S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC
C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1
S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
Field of research: Epigenetics, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000
Target: USP37
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat