USP21 antibody - 100 µg

Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ubiquitin specific peptidase 21
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 63 kDa
Uniprot: Q9UK80
Gene id: 27005
Background: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A
TIP5 leading to its stabilization(PubMed:26100909).
Field of research: Epigenetics, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Target: USP21
Purification: Immunogen affinity purified
Reactivity: Human