USP1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 8F7
Isotype: IgG1
Immunogen: ubiquitin specific peptidase 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 90 kDa
Uniprot: O94782
Gene id: 7398
Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Field of research: Epigenetics, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:10000; IHC: 1:20-1:200
Target: USP1
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 8F7
Isotype: IgG1
Immunogen: ubiquitin specific peptidase 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 90 kDa
Uniprot: O94782
Gene id: 7398
Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Field of research: Epigenetics, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:10000; IHC: 1:20-1:200
Target: USP1
Purification: Protein A+G purification
Reactivity: Human