UBR2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ubiquitin protein ligase E3 component n-recognin 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66 kDa
Uniprot: Q8IWV8
Gene id: 23304
Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Field of research: Epigenetics, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC
Dilution: WB: 1:200-1:2000; IF:1:10-1:100; IHC: 1:20-1:200
Target: UBR2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ubiquitin protein ligase E3 component n-recognin 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66 kDa
Uniprot: Q8IWV8
Gene id: 23304
Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Field of research: Epigenetics, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC
Dilution: WB: 1:200-1:2000; IF:1:10-1:100; IHC: 1:20-1:200
Target: UBR2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse