UACA antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: uveal autoantigen with coiled-coil domains and ankyrin repeats
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 163 kDa
Uniprot: Q9BZF9
Gene id: 55075
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3
galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1(By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation(By similarity).
Field of research: Immunology, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:10000; IF: 1:20-1:200
Target: UACA
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: uveal autoantigen with coiled-coil domains and ankyrin repeats
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 163 kDa
Uniprot: Q9BZF9
Gene id: 55075
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3
galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1(By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation(By similarity).
Field of research: Immunology, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:10000; IF: 1:20-1:200
Target: UACA
Purification: Immunogen affinity purified
Reactivity: Human, Mouse