TWSG1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: twisted gastrulation homolog 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35 kDa
Uniprot: Q9GZX9
Gene id: 57045
Background: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development(By similarity).
Field of research: Neuroscience, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: TWSG1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: twisted gastrulation homolog 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35 kDa
Uniprot: Q9GZX9
Gene id: 57045
Background: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development(By similarity).
Field of research: Neuroscience, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: TWSG1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat