NKX2-1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: NK2 homeobox 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 42 kDa
Uniprot: P43699
Gene id: 7080
Background: NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea(BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress(CHNRD). The antibody is specific to NKX2-1.
Field of research: Cancer, Immunology, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: NKX2-1
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: NK2 homeobox 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 42 kDa
Uniprot: P43699
Gene id: 7080
Background: NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea(BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress(CHNRD). The antibody is specific to NKX2-1.
Field of research: Cancer, Immunology, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: NKX2-1
Purification: Immunogen affinity purified
Reactivity: Human