TRPC4AP antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 1C0
Isotype: IgG1
Immunogen: transient receptor potential cation channel, subfamily C, member 4 associated protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 91 kDa
Uniprot: Q8TEL6
Gene id: 26133
Background: Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: TRPC4AP
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 1C0
Isotype: IgG1
Immunogen: transient receptor potential cation channel, subfamily C, member 4 associated protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 91 kDa
Uniprot: Q8TEL6
Gene id: 26133
Background: Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: TRPC4AP
Purification: Protein A+G purification
Reactivity: Human