TP53INP1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: tumor protein p53 inducible nuclear protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: Q96A56
Gene id:
Background: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1
L2, MAP1LC3A
B
C and regulates autophagy. Acts as an antioxidant and plays a major role in p53
TP53-driven oxidative stress response. Possesses both a p53
TP53-independent intracellular reactive oxygen species(ROS) regulatory function and a p53
TP53-dependent transcription regulatory function. Positively regulates p53
TP53 and p73
TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53
TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, IF
Dilution: IHC: 1:20-1:200; IF: 1:20-1:200
Target: TP53INP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: tumor protein p53 inducible nuclear protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: Q96A56
Gene id:
Background: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1
L2, MAP1LC3A
B
C and regulates autophagy. Acts as an antioxidant and plays a major role in p53
TP53-driven oxidative stress response. Possesses both a p53
TP53-independent intracellular reactive oxygen species(ROS) regulatory function and a p53
TP53-dependent transcription regulatory function. Positively regulates p53
TP53 and p73
TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53
TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, IF
Dilution: IHC: 1:20-1:200; IF: 1:20-1:200
Target: TP53INP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat