TFIP11 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 3H5
Isotype: IgG1
Immunogen: tuftelin interacting protein 11
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 97 kDa
Uniprot: Q9UBB9
Gene id: 24144
Background: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
Field of research: Neuroscience, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:50-1:500
Target: TFIP11
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 3H5
Isotype: IgG1
Immunogen: tuftelin interacting protein 11
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 97 kDa
Uniprot: Q9UBB9
Gene id: 24144
Background: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
Field of research: Neuroscience, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:50-1:500
Target: TFIP11
Purification: Protein A+G purification
Reactivity: Human