TESC antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: tescalcin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 25-30 kDa
Uniprot: Q96BS2
Gene id: 54997
Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)
H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1
NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Field of research: Signal Transduction, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: TESC
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: tescalcin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 25-30 kDa
Uniprot: Q96BS2
Gene id: 54997
Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)
H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1
NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Field of research: Signal Transduction, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: TESC
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat