TELO2 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 8B6
Isotype: IgG2a
Immunogen: TEL2, telomere maintenance 2, homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 92 kDa
Uniprot: Q9Y4R8
Gene id: 9894
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, IF, IP, WB
Dilution: WB: 1:1000-1:4000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: TELO2
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 8B6
Isotype: IgG2a
Immunogen: TEL2, telomere maintenance 2, homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 92 kDa
Uniprot: Q9Y4R8
Gene id: 9894
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, IF, IP, WB
Dilution: WB: 1:1000-1:4000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: TELO2
Purification: Protein A+G purification
Reactivity: Human