Talpid3 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: KIAA0586
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: E9PV87
Gene id: 76967
Background: Required for ciliogenesis and sonic hedgehog
SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:50-1:500
Target: Talpid3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

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