SUN1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: unc-84 homolog A(C. elegans)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 90 kDa
Uniprot: O94901
Gene id: 6821
Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: SUN1
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: unc-84 homolog A(C. elegans)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 90 kDa
Uniprot: O94901
Gene id: 6821
Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: SUN1
Purification: Immunogen affinity purified
Reactivity: Human