STOML2 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 5D10
Isotype: IgG2a
Immunogen: stomatin(EPB72)-like 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 39 kDa
Uniprot: Q9UJZ1
Gene id: 30968
Background: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
Field of research: cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:10000; IP: 1:500-1:1000; IHC: 1:50-1:500
Target: STOML2
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 5D10
Isotype: IgG2a
Immunogen: stomatin(EPB72)-like 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 39 kDa
Uniprot: Q9UJZ1
Gene id: 30968
Background: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
Field of research: cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:10000; IP: 1:500-1:1000; IHC: 1:50-1:500
Target: STOML2
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat