STIM1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 4G6
Isotype: IgG2a
Immunogen: stromal interaction molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 77 kDa
Uniprot: Q13586
Gene id: 6786
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110
STIMATE, leading to promote STIM1 conformational switch(By similarity).
Field of research: Neuroscience, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000 IHC: 1:50-1:500
Target: STIM1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 4G6
Isotype: IgG2a
Immunogen: stromal interaction molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 77 kDa
Uniprot: Q13586
Gene id: 6786
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110
STIMATE, leading to promote STIM1 conformational switch(By similarity).
Field of research: Neuroscience, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000 IHC: 1:50-1:500
Target: STIM1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat