SPO11 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: SPO11 meiotic protein covalently bound to DSB homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 55-70 kDa
Uniprot: Q9Y5K1
Gene id: 23626
Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: SPO11
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: SPO11 meiotic protein covalently bound to DSB homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 55-70 kDa
Uniprot: Q9Y5K1
Gene id: 23626
Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: SPO11
Purification: Immunogen affinity purified
Reactivity: Human, Mouse