SPAG8 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: sperm associated antigen 8
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 56-65 kDa
Uniprot: Q99932
Gene id: 26206
Background: Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau(By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida(By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2
M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis(PubMed:19548270). May play a role in fertility and microtubule formation through interaction with RANBP9(PubMed:10500252).
Field of research: Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: SPAG8
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

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