SMYD2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: SET and MYND domain containing 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50 kDa
Uniprot: Q9NRG4
Gene id: 56950
Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53
TP53 and RB1. Specifically methylates histone H3 'Lys-4'(H3K4me) and dimethylates histone H3 'Lys-36'(H3K36me2). Shows even higher methyltransferase activity on p53
TP53. Monomethylates 'Lys-370' of p53
TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53
TP53. Monomethylates RB1 at 'Lys-860'.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: SMYD2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: SET and MYND domain containing 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50 kDa
Uniprot: Q9NRG4
Gene id: 56950
Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53
TP53 and RB1. Specifically methylates histone H3 'Lys-4'(H3K4me) and dimethylates histone H3 'Lys-36'(H3K36me2). Shows even higher methyltransferase activity on p53
TP53. Monomethylates 'Lys-370' of p53
TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53
TP53. Monomethylates RB1 at 'Lys-860'.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: SMYD2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse