SMN1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 3D2
Isotype: IgG1
Immunogen: survival of motor neuron 2, centromeric
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: Q16637
Gene id:
Background: The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:1000-1:6000; IF: 1:50-1:500
Target: SMN1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 3D2
Isotype: IgG1
Immunogen: survival of motor neuron 2, centromeric
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: Q16637
Gene id:
Background: The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:1000-1:6000; IF: 1:50-1:500
Target: SMN1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat