MIEF1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Smith-Magenis syndrome chromosome region, candidate 7-like
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q9NQG6
Gene id: 54471
Background: Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IP
Dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Target: MIEF1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Smith-Magenis syndrome chromosome region, candidate 7-like
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q9NQG6
Gene id: 54471
Background: Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IP
Dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Target: MIEF1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat