SIRT1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 6A1
Isotype: IgG1
Immunogen: sirtuin(silent mating type information regulation 2 homolog) 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 130 kDa
Uniprot: Q96EB6
Gene id: 23411
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Field of research: Neuroscience, Stem Cells, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:5000; IP: 1:500-1:2000 for WB; IHC: 1:20-1:200
Target: SIRT1
Purification: Protein A+G purification
Reactivity: Human, Mouse
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Clonality: Monoclonal
Clone: 6A1
Isotype: IgG1
Immunogen: sirtuin(silent mating type information regulation 2 homolog) 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 130 kDa
Uniprot: Q96EB6
Gene id: 23411
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Field of research: Neuroscience, Stem Cells, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:5000; IP: 1:500-1:2000 for WB; IHC: 1:20-1:200
Target: SIRT1
Purification: Protein A+G purification
Reactivity: Human, Mouse