SGK3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: serum
glucocorticoid regulated kinase family, member 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 57 kDa
Uniprot: Q96BR1
Gene id: 23678
Background: Serine
threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A
ENAC and SCN5A, K(+) channels: KCNA3
KV1.3, KCNE1, KCNQ1 and KCNH2
HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)
dicarboxylate cotransporter: SLC13A2
NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2
NAPI-2B, amino acid transporters: SLC1A5
ASCT2 and SLC6A19, glutamate transporters: SLC1A3
EAAT1, SLC1A6
EAAT4 and SLC1A7
EAAT5, glutamate receptors: GRIA1
GLUR1 and GRIK2
GLUR6, Na(+)
H(+) exchanger: SLC9A3
NHE3, and the Na(+)
K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH
AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: SGK3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: serum
glucocorticoid regulated kinase family, member 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 57 kDa
Uniprot: Q96BR1
Gene id: 23678
Background: Serine
threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A
ENAC and SCN5A, K(+) channels: KCNA3
KV1.3, KCNE1, KCNQ1 and KCNH2
HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)
dicarboxylate cotransporter: SLC13A2
NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2
NAPI-2B, amino acid transporters: SLC1A5
ASCT2 and SLC6A19, glutamate transporters: SLC1A3
EAAT1, SLC1A6
EAAT4 and SLC1A7
EAAT5, glutamate receptors: GRIA1
GLUR1 and GRIK2
GLUR6, Na(+)
H(+) exchanger: SLC9A3
NHE3, and the Na(+)
K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH
AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: SGK3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat