SCIN antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: scinderin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 75-80 kDa
Uniprot: Q9Y6U3
Gene id: 85477
Background: Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1
2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes(By similarity).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:5000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: SCIN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: scinderin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 75-80 kDa
Uniprot: Q9Y6U3
Gene id: 85477
Background: Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1
2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes(By similarity).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:5000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: SCIN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat