RASGRP2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: RAS guanyl releasing protein 2(calcium and DAG-regulated)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 48 kDa
Uniprot: Q7LDG7
Gene id: 10235
Background: Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1
CHRM1 signaling pathway.
Field of research: Neuroscience, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: RASGRP2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: RAS guanyl releasing protein 2(calcium and DAG-regulated)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 48 kDa
Uniprot: Q7LDG7
Gene id: 10235
Background: Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1
CHRM1 signaling pathway.
Field of research: Neuroscience, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: RASGRP2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse