CRADD antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CASP2 and RIPK1 domain containing adaptor with death domain
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 23 kDa
Uniprot: P78560
Gene id:
Background: RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL
TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200
Target: CRADD
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: CASP2 and RIPK1 domain containing adaptor with death domain
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 23 kDa
Uniprot: P78560
Gene id:
Background: RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL
TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200
Target: CRADD
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat