PTGES3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: prostaglandin E synthase 3(cytosolic)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 21-23 kDa
Uniprot: Q15185
Gene id: 10728
Background: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1
PHD2, leading to recruit EGLN1
PHD2 to the HSP90 pathway(PubMed:24711448).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, IP, WB, FC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
Target: PTGES3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: prostaglandin E synthase 3(cytosolic)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 21-23 kDa
Uniprot: Q15185
Gene id: 10728
Background: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1
PHD2, leading to recruit EGLN1
PHD2 to the HSP90 pathway(PubMed:24711448).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, IP, WB, FC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
Target: PTGES3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat