POFUT2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: protein O-fucosyltransferase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa, 50 kDa
Uniprot: Q9Y2G5
Gene id: 23275
Background: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S
T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: POFUT2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: protein O-fucosyltransferase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa, 50 kDa
Uniprot: Q9Y2G5
Gene id: 23275
Background: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S
T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: POFUT2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat