PICK1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: protein interacting with PRKCA 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-55 kDa
Uniprot: Q9NRD5
Gene id: 9463
Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1
ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2
3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2
3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression(LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2
3 complex activator WASL
N-WASP function.
Field of research: Neuroscience, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB, IP, IF
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: PICK1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: protein interacting with PRKCA 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-55 kDa
Uniprot: Q9NRD5
Gene id: 9463
Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1
ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2
3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2
3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression(LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2
3 complex activator WASL
N-WASP function.
Field of research: Neuroscience, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB, IP, IF
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: PICK1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat