PAG1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: phosphoprotein associated with glycosphingolipid microdomains 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-60 kDa
Uniprot: Q9NWQ8
Gene id: 55824
Background: Negatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: PAG1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: phosphoprotein associated with glycosphingolipid microdomains 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-60 kDa
Uniprot: Q9NWQ8
Gene id: 55824
Background: Negatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: PAG1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse