MAPK14 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 6D2
Isotype: IgG1
Immunogen: mitogen-activated protein kinase 14
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: Q16539
Gene id: 1432
Background: MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Field of research: Immunology, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:4000; IHC: 1:100-1:400
Target: MAPK14
Purification: Protein A+G purification
Reactivity: Human, Pig
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Clonality: Monoclonal
Clone: 6D2
Isotype: IgG1
Immunogen: mitogen-activated protein kinase 14
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 38 kDa
Uniprot: Q16539
Gene id: 1432
Background: MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Field of research: Immunology, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:4000; IHC: 1:100-1:400
Target: MAPK14
Purification: Protein A+G purification
Reactivity: Human, Pig