CDKN2A antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: cyclin-dependent kinase inhibitor 2A(melanoma, p16, inhibits CDK4)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 16-18 kDa
Uniprot: P42771
Gene id: 1029
Background: CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.
Field of research: Metabolism, Immunology, Cell Division and Proliferation, Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IP, IHC, FC
Dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200
Target: CDKN2A
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: cyclin-dependent kinase inhibitor 2A(melanoma, p16, inhibits CDK4)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 16-18 kDa
Uniprot: P42771
Gene id: 1029
Background: CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.
Field of research: Metabolism, Immunology, Cell Division and Proliferation, Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IP, IHC, FC
Dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200
Target: CDKN2A
Purification: Immunogen affinity purified
Reactivity: Human