ORAI1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 8C0
Isotype: IgG1
Immunogen: ORAI calcium release-activated calcium modulator 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 32 kDa
Uniprot: Q96D31
Gene id: 84876
Background: Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB,IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:500
Target: ORAI1
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 8C0
Isotype: IgG1
Immunogen: ORAI calcium release-activated calcium modulator 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 32 kDa
Uniprot: Q96D31
Gene id: 84876
Background: Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB,IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:500
Target: ORAI1
Purification: Protein A+G purification
Reactivity: Human